The Albert Einstein College of Medicine Nathan Shock Center

• Wei Chen, Albert Einstein College of Medicine: Calciprotein Particles and Vascular Aging
• Dibyadeep Datta, Yale University: Proteomic Evaluation of Macroautophagy and Endolysosomal Dysfunction Following Chronic 2- MPPA Intervention in Aged Non-Human Primates
• Nicholas Sibinga, Albert Einstein College of Medicine: Aging and Vascular Stiffness
  

The Jackson Laboratory Nathan Shock Center

• Monika Bambouskova, Washington University: Defining immunometabolic determinants of aging in adipose tissue
  
• Isabel Beerman, National Institute on Aging: Characterization of early hematopoietic progenitors during aging in UM-HET3 mice
• Andrew Ludlow, University of Michigan: Impact of age on alternative splicing isoform generation

San Diego Nathan Shock Center

Year 5 Awards

• Axelle Bouche, UC San Diego: Exploring sexual dimorphism in aging-associated changes of pelvic skeletal muscle stem cells
  
• Shiri Gur-Cohen, UC San Diego: Decoding the Aged Stem Cell Ecosystem in Regeneration and Tissue Repair
• Jose Vieira-Isola, The Oklahoma Medical Research Foundation: Exploring mTOR activity & immune cell interactions in the aging ovary using spatial transcriptomics

The University of Alabama at Birmingham Nathan Shock Center

• Robert Mankowski & Peter Morris, UAB Medicine: Senescence as a link to a chronic bioenergetic dysfunction in the critical illness-induced physical function loss and the effect of age
  
• Mohamed Khass, UAB School of Dentistry: The influence of progenitor B cell product, λ5 on Mesenchymal stem cell aging and fate determination
• Christopher Wiley, Tufts University: Assessment of cell-free mitochondrial DNA in CALERIE study participants

Oklahoma Nathan Shock Center

• Laszlo Balint, University of North Carolina: Characterization of organ-specific changes in the lymphatic mtDNA during aging
  
• Doris Benbrook, The University Of Oklahoma Health Sciences Center: Aging changes in fallopian tubes, the origin of high grade serous ovarian cancer
• Marisol Castillo-Castrejon, The University Of Oklahoma Health Sciences Center: The role of sex hormones in the adaptive immunity of menopausal women
• Theaodore DeConne, Wake Forest University: The effect of senolytics on T-cell senescence
• Jaya Krishnan, Oklahoma Medical Research Foundation: Investigating mechanisms underlying oxidative stress resistance in cavefish Astyanax mexicanus
• Timothy Rhoads, University of Wisconsin-Madison: TREX, RNA processing and caloric restriction
• Dhandendra Tomar, Wake Forest University: IMS proteases in mitochondrial proteostasis
• Celina Valencia, University of Arizona: Investigating menopause, inflammation, and dual tissue DANm for novel insights in reproductive aging
  

USC-Buck Nathan Shock Center

Year 4 Awards

• Samuel Bailin, Vanderbilt University Medical Center: Adipose Tissue Aging and Senescence in Persons with HIV
• Jordan Burton, Buck Institute for Research on Aging: Unveiling the Molecular Basis of Longevity in Honey Bee Flight Muscle
• Sara Espinoza, University of Texas San Antonio: Mitochondrial Microproteins Response to Metformin

Year 5 Awards

• Samuel Bloom, Salk Institute: Defining the secretome associated with replicative crisis
• Eric Goetzman, University of Pittsburgh: Effect of ganglioside deficiency on brain cell signaling and the microglial secretome

San Antonio Nathan Shock Center

• Kevin Koronowski, UT Health San Antonio: Hepatocyte Secreted Proteins in the Blood as Functions of Age and Circadian Time
  
• Valentina Garbarino, UT Health San Antonio: Effect of lactoferrin on age-related hippocampal transcript and protein outcomes
  
• Chia-Nung Hung, UT Health San Antonio: Aging-induced OXPHOS dysfunction causes metastatic macrophage-tumor hybrid cells

The University of Washington Nathan Shock Center

• Xu Chen, University of California San Diego School of Medicine: Elucidating Beta Hydroxybutyrate-Protein Interactions in Age-related Neurodegenerative Disease
  
• Cory Baumann, Ohio University: Decoding the Age-Exercise Paradox: Insights into Muscle Adaptations and Aging
• Joshua Drake, Virginia Tech: Phospho-proteomic assessment of the acute response to exercise in skeletal muscle between 3- and 24-month old mice
• Aditi Gurkar, University of Pittsburgh: Examining DNA damage induced dysregulation of the pantothenate pathway in cardiac health
• Molly Burke, Oregon State University: Understanding potential trade-offs between replicative lifespan and late-life sexual fertility in Saccharomyces cerevisiae
• James Colbert, University of Colorado Anschutz Medical Campus: Utilizing explainable artificial intelligence to identify gut microbial metagenomic features that drive exaggerated aging-associated sepsis severity
• Ahmed Lawan, University of Alabama in Huntsville: Characterize adipose tissue metabolome of aged MKP-2-deficient mice