San Antonio Nathan Shock Center
San Antonio, TX
Specialized Core Areas
Administrative and Program Enrichment Core
Services
- Seminars, meetings and conferences
- Weekly Aging Research Seminars, Journal Club and an annual Conference on Aging
Research and Development Core
Services
- Runs a pilot project program to enable investigators to take advantage of the expertise of the cores at the San Antonio Shock Center. Please email for details.
Aging Animal Models and Longevity Assessment Core
Services
- Breed and maintain rodent colonies
- Lifespan studies in rodents
- Provide animal models for baseline pilot studies
- Provide diets containing rapamycin and other drugs
- Educate staff in animal husbandry and experimental design
GeroMetabolism Core
Services
- Provide intellectual and instrumental/technical services to the scientific community on the selection and performance of functional assays in rodents that aim to increase our knowledge about mechanisms that control age-related changes in function at the tissue, organ, and whole body levels, in the context of normal aging and in relation to age-related diseases
- Provide expertise and assistance to investigators with an interest in aging-related questions in the design and execution, as well as data analysis and interpretation on experimental measures
Pathology Core
Services
- End of life and cross-sectional pathology in rodents and other species maintained by the Aging Animal and Longevity Assessment Core
- Quantitative morphometric analyses by 3D and 2D imaging
- Develop a database and tissue archive of histopathology
Core Leader
Yuji Ikeno, MD, PhD
EmailPharmacology and Drug Design Core
Services
- Developing and validating bioanalytical assays for drugs and small molecules
- Designing and creating usable, effective dosage forms
- Measuring and confirming concentrations and stability of drugs in dosage forms
- Quantifying and confirming drug concentrations in blood and tissues
- Informing investigators on the process of dosage form development
- Recommending pharmacologic approaches, such as level/timing of doses in studies
- Proposing and justifying pharmacokinetic experiments if needed
- Assisting in interpretation of data and preparation of papers and grants
